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In addition to inducing the main phenotype of ferroptosis, the loss of GPX4 can in some cells trigger apoptosis, necroptosis, pyroptosis, or parthanatos, which mediates or accelerates developmental defects, tissue damage, and sterile inflammation

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Studies have shown that 5-amino-1mq significantly promotes the differentiation of cultured myoblasts and accelerates myotube formation

doi:10.1016/j.dsx.2020.01.002 Santos HO, da Silva GAR