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Many researchers use both: topical for targeted flare management and systemic for baseline support

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People who are pregnant or breastfeeding People taking prescription medications NAC may interact with certain medications, including nitroglycerin and other nitrate-containing drugs, potentially increasing the risk of headaches, dizziness, and low blood pressure.26 Because NAC is also being studied alongside treatments for respiratory disease, mental health conditions, fertility, and other medical concerns, it's a good idea to review any supplements with your healthcare provider before adding them to your routine

[51] Yang Y, Chen H, Weng S, Pan T, Chen W, Wang F, et al