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In the original mouse work it was described as well-tolerated, but that is the limit of the in-vivo safety evidence, and it is mouse-only

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I think with all these new modalities, this happened with dry needling and then BFR too had its thing, is it starts to get really popular and you hear a lot of buds around the mechanismic studies, but at the end of the day, the first thing that we have to take care of is safety

Likewise, these might be the therapeutic effects against those induced by the various muscle disabilities, and the large variety of different noxious events

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