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Without that deficit or activity, the effect is minimal

J Neuroimmune Pharmacol 7(1):4259 Motaghinejad M, Mashayekh R, Motevalian M, Safari S (2021) The possible role of CREB-BDNF signaling pathway in neuroprotective effects of minocycline against alcohol-induced neurodegeneration: molecular and behavioral evidences

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These challenges have led to the development of more stable analogues, improved delivery systems, and increased interest in smaller peptide fragments that retain bioactivity while minimizing these drawbacks [9]