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Furthermore, we performed the cellular thermal shift assay (CETSA) at a concentration of 60 M of QCT by its predicted Ki value (60.351 M), and the results indicated that EGFR expression decreased with rising temperature in both control and QCT groups, with lower expression observed in the control group (Fig

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Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial