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Notably, both erastin and sorafenib induce ferroptosis by inhibiting System Xc-'s activity [146]

Advanced fibrosis is in these models usually achieved when combining nutritional intervention with a second proinflammatory hit

M.BreaG.et al

Brain 5 , 35

Identification and expression of iron regulators in human synovium: evidence for upregulation in haemophilic arthropathy compared to rheumatoid arthritis, osteoarthritis, and healthy controls