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- GHK-Cu is a copper-binding research peptide studied in models involving skin biology, collagen-associated pathways, extracellular matrix research, wound-response signaling, hair follicle pathway models, angiogenesis, antioxidant response, and tissue-remodeling biology

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This may be important since BPC 157 itself not only increased Vegfr2 expression in vascular endothelial cells but also immediately triggered the internalization of Vegfr2 and subsequent phosphorylation of Vegfr2 , Akt, and Nos3 signaling pathways without other known ligands or shear stress (Hsieh et al., 2017)