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For home monitoring, standardized questionnaires such as the Michigan Neuropathy Screening Instrument (MNSI) and the Neuropathy Total Symptom Score (NTSS-6) provide structured self-assessment tools

As per Bradford Hills criteria 41 , the biological plausibility through GLP-1R expression in the nervous system and temporal consistency in time-to-onset analysis support potential causality, but confounding factors inherent to spontaneous reporting systems preclude definitive conclusions

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