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67 PEG-loxenatide, Chinas first long-acting GLP-RA product, was approved for marketing in China in May 2019

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Subgroup analyses indicated that individuals with a BMI of 35 or greater and female participants experienced greater percentage reductions in weight than those with lower BMI or male participants

These findings were further corroborated within the Lifelines Cohort, where results showed sex- and duration-specific DNA methylation changes in women exposed to intermediate-term NSW (10-16 years), enriched in pathways related to circadian regulation and cellular senescence