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doi: 10.1016/j.toxlet.2014.11.027

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NICE obesity guidance (CG189) recommends multicomponent interventions addressing diet, physical activity, and behaviour change as first-line management

Additionally, oxidative stress and autoimmunity in vitiligo create a less favorable microenvironment for the development of skin cancer, including melanoma.75 Environmental agents as disease activators Environmental factors influence the onset or worsening of vitiligo in susceptible individuals (Table 5)