In epithelial cells macropinocytosis is strongly connected to oncogenic activation and actin cytoskeleton rearrangements which are generally involved in cancer progression, and for this reason inhibition of macropinocytosis as means to prevent cholesterol uptake could be a useful approach in cancers that can activate it
For GSH-pathway measurements, each colored symbol represents an individual patient (circles = HC, triangles = M/MA, squares = SA) or individual human cell line, which can be followed through multiple figures
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