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In contrast, Moscat and Diaz-Meco have shown that p62 activates Raptor of mTORC1 leading to the inhibition of autophagy [280]

In summary, as an important factor of aging, oxidative stress can also mediate telomere damage in the ovaries and cause ovarian aging (Figure 1)

Hydrophilic compounds dissolve well in sterile water or bacteriostatic water, while acidic peptides may require basic buffers before dilution

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Discussion The use of antioxidants as a concomitant therapy has been proven useful for the management of ASD symptoms (Fraguas et al., 2019), however, their impact as monotherapy remains unclear