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Interestingly, external iron supplementation has been shown to inhibit M1 polarization by downregulating proinflammatory mediators and iNOS expression through STAT1 inhibition, without impairing phagocytic capacityM1 (108)

Several studies have reported symptomatic improvements in CFS/ME patients who adopt Mediterranean-style diets or increase their intake of prebiotic-rich foods (Kitami et al., 2020

This crucial reaction occurs at the active site of GPX4, distinguished by the presence of a selenocysteine residue that is vital for its activity (143)

twofold, P = 0.0008)

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