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Sex-dependent effects emerged specifically in a large Korean study with anxious population, where men exhibited reduced alpha diversity while women showed no changes (Kim et al., 2023)

On the other hand, the inverse association of riboflavin with plasma homocysteine levels can also be attributed to riboflavins interaction with methyltetrahydrofolate reductase (MTHFR), another peculiar flavoprotein involved in follicular activity, embryo quality and pregnancy success 90,91,92

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