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The 1991 study that employed the transgenic albumin-urokinase type plasminogen activator (Alb-uPA) mouse model is recognized as one of the early landmark studies in which genetic manipulation was used to investigate liver regeneration

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NF-B inflammatory pathway and the janus kinase pathway (JAK)/signal transducers and activators of transcription 3 (STAT3) pathway have been associated with the development of GDM [22]

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doi: 10.1111/j.1470-9465.2004.00845.x 95 Dita MB