Protocol design is based on skin tone, pigmentation severity, treatment goals, overall health profile, and any concurrent medications or conditions
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Despite these reductions, FBG and HOMA-IR levels in Group III remained significantly higher than in Group I, however, serum insulin differences between Groups I and III were not statistically significant (P = 0.23)
To look for differences in changes between the CRWP and placebo groups for the psychological measurements, a series of paired and unpaired t -tests were conducted using a Bonferroni adjustment