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Step 7: Inspect the solution

A placebo-controlled, double-blind trial of DFO in early-stage PD showed reduced iron accumulation in the SN and delayed motor symptom progression (271)

& Irani, D

Haigis MC, Mostoslavsky R, Haigis KM, Fahie K, Christodoulou DC, Murphy AJ, Valenzuela DM, Yancopoulos GD, Karow M, Blander G, Wolberger C, Prolla TA, Weindruch R, Alt FW, Guarente L

We further investigated the effect of erucamide on myeloid cells through TMEM19 by analyzing bulk RNA sequencing (RNA-seq) in iPS cell-MPCs treated with erucamide with TMEM19 knocked down