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Two isozymes of heme oxygenase play distinct role: HMOX1 , an inducible enzyme regulated by oxidative stress and transcription factors like NRF2 , and HMOX2 , a constitutively expressed form involved in normal cellular homeostasis [16]

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How Cagrilintide Works (Mechanism of Action) Cagrilintide functions as a long acting synthetic analog of the peptide hormone amylin and is primarily studied as an agonist of amylin receptor complexes in experimental systems