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When ejected in the vicinity of the neurons with a glass pipet, compounds were diluted in a HEPES-based medium containing in mM: 138 NaCl, 2.5 KCl, 2 CaCl 2 , 1 MgCl 2 , 3 NaHCO 3 , 1.25 NaH 2 PO 4 , 10 HEPES, 12 glucose, pH 7.4 with NaOH