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We typically recommend a 24 week break after 812 weeks on for chronic protocols the necessity isn't fully established, but it's a sensible conservative approach for long-term use

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Start low: Begin around 250 g daily for 12 weeks Increase gradually: Up to 500 g twice daily if tolerated Cycle: 46 weeks on, then take 24 weeks off This approach supports tendon, muscle, or ligament healing without overloading the system

It slows gastric emptying significantly, which prolongs satiety after meals

For medical purposes, some doctors may recommend a weekly B12 shot for up to four weeks