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Under heat stress stimulation in both in vivo mouse models and in vitro cell experiments, the transport of p53 protein from the nucleus to the cytoplasm increases significantly, where it binds to Parkin protein, reducing Parkin's translocation from the cytoplasm to mitochondria

Arch Biochem Biophys 423:6673 Palamara AT, Perno CF, Aquaro S, Bue MC, Dini L, Garaci E (1996) Glutathione inhibits HIV replication by acting at late stages of the virus life cycle

Together with the inflammasome NLRP3, caspase-1 activates IL-1B

10,14 The light, modifier subunit provides a regulatory function, while GCLC is responsible for the catalytic activity, which conjugates sulfur-containing cysteine with glutamate, forming -glutamylcysteine

Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency