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Kannan S et al

Among them, GPX1-4 and 6 are selenocysteine-containing proteins

Cells were plated (2 10 7 cells per 150 mm plate) and grown for 24 h before transfection with Polyethylenimine (PEI, Sigma) according to the manufacturer's instructions

Historical data highlight the city's vulnerability, with notable droughts occurring in 1945, 1986-1989, 2004-2008, 2017 and 2023, along with major pluvial floods in 1995 and 2018

Another outstanding question Bluestone introduces is whether some of the patients experiencing specific irAEs have some aspects of the disease prior to immunotherapy (pre-existing condition) such that the treatment exacerbates it