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For example, a formulation that comprises sucrose acetate isobutyrate, a pharmaceutically acceptable solvent, one or more additives, and the active agent is administered at or near the round window membrane

The interpretation of these transcriptomic findings has been a continuing area of discussion, with some researchers viewing the broad effects as evidence of a regulatory function and others viewing them with caution given the difficulty of distinguishing direct effects from secondary consequences in such broad gene-expression landscapes

Tonolini and Magistrelli, 2017) as a common healing denominator providing simultaneous healing of different tissues

Capsules may appeal to patients who want convenience, while injections are often discussed for more direct delivery

Rigorously conducted Level 1 studies and cost/benefit analyses for these agents remain lacking at this time, though research is ongoing