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TB-500 has been shown to promote cell migration, angiogenesis, cytoskeletal reorganization, and anti-inflammatory signaling in preclinical models 1,2

It is hypothesized that following trauma, extracellular glutamate rises, initiating activation of N-methyl-D-aspartate (NMDA) receptors which promotes the influx of intracellular calcium ions (40)

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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

This chromosomal translocation causes the fusion of the ABL gene on chromosome 9 with the BCR gene on chromosome 22, giving rise to the BCR-ABL fusion gene