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Abstract Background Intracellular hydroperoxides are harmful reactive oxygen species that can cause damage

This leads to the release and subsequent cytoplasmic translocation of p53, which in turn activates a transcription-independent pro-apoptotic pathway, facilitating the selective clearance of senescent cells (Kong et al., 2025

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4 Research estimates that MCAS may affect up to 17% of the population to some degree, though many cases go undiagnosed

Naisbitt, Dean J