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established an animal model of lung injury from hypobaric hypoxia in a high altitude condition, which involved exposing SD rats to hypoxia at an altitude of 6000 m, with an ascent rate of 10 m/s, and continuous exposure to hypoxia for 3 days (Zeng et al., 2024)

Y., Micklethwaite, K

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Environ Int 137:105408

In addition, a decrease was seen in urinary volume, GFR, and filtration fraction in the FA group, followed by an increase in the concentrations of BUN and Cr