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REDEFINE 1, in adults with overweight or obesity without diabetes, reported 22.7% mean weight loss for the combination at 68 weeks on the on-treatment analysis, with 60% of combination participants reaching at least 20% loss and 23% reaching at least 30% (Aronne et al., 2025)

Summary Keywords molecular screening, bilirubin, favism, hemolytic anemia, neonatal jaundice, peroxiredoxin 2, Heinz bodies, G6PD Citation Lee HY, Ithnin A, Azma RZ, Othman A, Salvador A and Cheah FC (2022) Glucose-6-Phosphate Dehydrogenase Deficiency and Neonatal Hyperbilirubinemia: Insights on Pathophysiology, Diagnosis, and Gene Variants in Disease Heterogeneity

Circ J 72(1):116

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In agreement with our immunoblotting analysis, we observed an induction of CHAC1 under cystine starvation in CHAC1 expressing H1299 cells but not those subject to CRISPR/Cas9-mediated CHAC1 knockout 48 , indicating antibody specificity (Supplementary Fig