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Thrombospondins as key regulators of synaptogenesis in the central nervous system
Stronger Immune System GH enhances T-cell and macrophage function
The collapse of both astrocyte and microglia into pro-inflammatory states due to depletion of GSH, leading to sustained neuroinflammation and oxidative stress, is observed in many neurodegenerative diseases (Mandal et al., 2022
Primary search terminology included esculetin, 6,7-dihydroxycoumarin, and cichorigenin, combined with disease-specific or mechanism-based terms including esculetin AND inflammation, esculetin AND cancer, esculetin AND diabetes, esculetin AND antioxidant, coumarin AND bioavailability, and coumarin AND derivatives. Disease-specific searches incorporated relevant MeSH headings (neoplasms, cardiovascular diseases, diabetes mellitus, neurodegeneration, and hepatic/renal disorders)
Funding This study was supported by the Pamukkale University Scientific Research Projects Unit (project number: 2021TIPF003)
