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10.3389/fimmu.2023.1086078 Summary Keywords gut microbiota, metabolite, immune, NAFLD, NASH, botanical drug Citation Zhang Y, Liu L, Song R, Qu Z, Wang T, Liang L, Wang S, Zhang S, Li H and Wang H (2025) Potential mechanisms of natural metabolites and botanical drugs foumulae for the treatment of non-alcoholic fatty liver disease: targeting the gut microbiota to modulate the immune system