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Mild, transient fluid retention/edema and joint or muscle pain, each reported more often on MK-677 than placebo in the same trial, linked to elevated GH and IGF-1

As no relevant changes in e-GST levels were observed for bovine species (see Results section), all other mammalian species were tested without considering these physiological phases

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This taxon has also been described to decrease in subjects who later develop ulcerative colitis and to be inversely correlated, in its relative abundance, with fecal elastase and protease activity before disease onset