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We would like also to pinpoint the importance that in addition to metabolomic studies, in -depth studies on biochemical pathways using a multi-omics approaches in in vitro hepatotoxicity studies, such as transcriptomics, proteomics, and metabolomics, provides a more comprehensive understanding of the effects of xenobiotics at cellular level

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Ann Transl Med 6:467 Higgins T, Chaykin S, Hammond KB, Humbert JR (1972) Trimethylamine N-oxide synthesis: a human variant