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Although there is a robust heat shock response of Hsp70 in endometriosis (117), ROS damages heat shock proteins impeding HSP-mediated re-folding of polypeptides misfolded and otherwise damaged due to oxidative stress

ChaC-like proteins are generally characterized by their highly conserved GCT domain, which enables them to degrade -glutamyl amino acids

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Vitamin B12 may also play an important role in bone health, as studies have shown that low blood levels of B12 can be associated with an increased risk of osteoporosis in women

Proc Natl Acad Sci USA 93:1442814433 Winterbourn CC, Metodiewa D (1994) The reaction of superoxide with reduced glutathione