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Methylene blue is used to reduce oxidative stress, enhance mitochondrial respiration as an electron carrier, and promote the clearance of tau proteins (a group of proteins primarily found in the brain that play a critical role in maintaining the structure and function of neurons) and amyloid plaques (abnormal deposits of a protein called beta-amyloid (A) in the brain, a hallmark feature of Alzheimer's disease and other neurodegenerative conditions), which are implicated in diseases like Alzheimers, Parkinsons, and Huntingtons disease

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PLoS ONE 16(11):e0253780

9i), suggesting that cotargeting GLUT1 and YBX1 confers selective synthetic lethality and has a potentially broad therapeutic effect

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