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High expression of nicotinamide N-methyltransferase in patients with obesity and insulin resistance

Schaller M, Dirschka T, Lonne-Rahm SB, et al

You may wish to discuss testing with a healthcare professional if you: Experience ongoing unexplained fatigue Follow a vegan or vegetarian diet Have a history of gastrointestinal surgery or digestive conditions Have previously been diagnosed with low B12 Have symptoms such as numbness, tingling, or cognitive changes Testing helps determine whether B12 injections are appropriate or whether another cause should be investigated

In this Review, we summarize the data from CVOTs of GLP1R agonists in patients with T2DM and describe the actions of GLP1R agonists on the heart and blood vessels