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Other replacement strategies include the substitution of naphthyl rings to heterobiaryls 3 and 4 such as quinoline, isoquinoline 16 , phthalazine 16 indene 17 , benzimidazole 18 , benzothiophene 19 , indole 20 and, more recently, benzazaborinine 5 21

Data from scRNA-seq and Western blot analyses of kidney tissues from mice with oxalate-induced AKI, along with observations of primary PTECs treated with CaOX, either alone or co-incubated with ferroptosis-specific inhibitors, demonstrated the occurrence of ferroptosis in renal tubular cells within the oxalate-induced AKI model

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