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In the RTgill-W1 cells, treatment with rotenone led to GSH depletion, while addition of the GSH precursor NAC, significantly reduced rotenone induced ROS production and dell death

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No lethal dose has been established for BPC-157 in animal models, and it demonstrates consistent protection against drug-induced and surgical organ damage. Perovic, D

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Bioorg Chem 9:253260 Akaike T, Ida T, Wei FY, Nishida M, Kumagai Y, Alam MM, Ihara H, Sawa T, Matsunaga T, Kasamatsu S, Nishimura A, Morita M, Tomizawa K, Nishimura A, Watanabe S, Inaba K, Shima H, Tanuma N, Jung M, Fujii S, Watanabe Y, Ohmuraya M, Nagy P, Feelisch M, Fukuto JM, Motohashi H (2017) Cysteinyl-tRNA synthetase governs cysteine polysulfidation and mitochondrial bioenergetics