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Specifically, bioactive molecules such as leukotrienes and prostaglandins produced during AA metabolism via LOX and COX can directly or indirectly increase NOX complex activity, leading to the catalysis of intracellular ROS synthesis, including O , thereby participating in the regulation of oxidative stress and cell signalling pathways [15]

Thomas MB, Moran N, Smart K, Crean S

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Micronization is a process of reducing the average diameter of particles of a solid material