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Experimental evidence indicates that butein reduces ROS generation and suppresses IL-6 and intercellular adhesion molecule-1 (ICAM-1) expression in TNF--stimulated HaCaT model

Theranostics 10 , 79067920 (2020)

Red cell production requires many substrates, not the least of which is protein

It can be triggered by sun exposure, hormonal changes, or genetic factors

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