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They are not FDA-approved drugs that undergo the same rigorous mass-manufacturing testing
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A minimally-masked inactive prodrug of panobinostat that is bioorthogonally activated by gold chemistry
[DOI] [PubMed] [Google Scholar] 160.Smith L., Tracy D.K., Giaroli G
Ferric iron (Fe 3+ ) is stored within ferritin in the cytoplasm, whereas Fe 2+ for ferroptosis induction is either imported via CD44 from the extracellular compartment [22] or provided via lysosomal ferritin degradation and subsequent reduction [23]
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