Serious Vitamin B12 deficiency can result in decreased number of red blood cells (anemia), stomach or intestinal diseases and permanent nerve damage
The reasons: Low lower limit : In most countries, the lower end of the standard vitamin B12 range (100-250 pg/mL) is too low, often missing severe deficiencies
This restoration of metabolic cofactor availability enables enhanced function of NAD+-dependent enzymes including sirtuins, poly(ADP-ribose) polymerases, and various deacetylases that regulate cellular metabolism, stress responses, and aging processes
Private clinics, with prescribing services and/or appropriate diagnostic options will usually recommend the use of hydroxocobalamin for B12 injections, however, cyanocobalamin is popular as a cheaper option
these treatments are not universally available to all patients