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Nausea (41%), diarrhea (23%), vomiting (20%), and constipation (18%) are the most frequently reported

Neuroinflammation also plays a critical role in the BBB breakdown that can lead to the fatal brain edema caused by diabetic ketoacidosis [36]

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Moreover, butyrate treatment improved intestinal barrier function by modulating TJ protein mRNA expression levels (Supplementary Fig

Patients who underwent revascularization treatment and developed a haemorrhagic transformation had a higher cumulative incidence of PSE (13.8% vs