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Beyond these preliminary observations, critical knowledge gaps and unaddressed questions hinder a comprehensive understanding of the ferroptosiskidney stone axis and its translational value

However, the choroid plexuses are disproportionately larger in the developing brain (Johansson et al., 2008) and transfer proteins across their epithelial cells (see below)

In particular, the treatment with the enzyme of glutathione-metal conjugates isolated from the bile of experimentally intoxicated animals was used as an evidence of their possible connectivity in the earlier toxicological studies [43,47]

These observations suggest that Cys-SSH and GSSH are produced under physiological conditions, while Cys-SS n H and GSS n H are unstable under such conditions