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Consider whether symptoms might indicate: Underlying conditions being unmasked or worsening Effects of other supplements or medications Lifestyle factors like inadequate sleep, poor nutrition, or excessive stress Infections or illnesses unrelated to peptide use If symptoms do not match the expected AOD 9604 profile, persist after discontinuation, or are accompanied by other concerning signs, investigate independently rather than assuming the peptide is responsible

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European Society of Endocrinology and Endocrine Society Joint Clinical Guideline: diagnosis and therapy of glucocorticoid-induced adrenal insufficiency

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Pyridoxine requirements are also increased during lactation