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Curcumin reduces OS and improves intestinal barrier integrity and mitochondrial functions by inducing Parkin-dependent mitophagy via AMPK (adenosine 5-monophosphate activated protein kinase) activation and TFEB (transcription factor EB) nuclear translocation (149)

J Chromatogr B 878:12071215

When your mucosal barrier is compromised, those tight junctions between cells in the intestinal walls open up, leading to small gaps where bacteria and other toxins can move freely

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