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3) 12-week-old male Sprague-Dawley rats were assigned to different treatment groups and used for animal experimentation in accordance with NIH guidelines

Hence, the action of the ascorbateglutathione cycle extends far beyond policing ROS signals, not least because this pathway serves to maintain the reduced states of the ascorbate and glutathione pools that fulfil important but divergent roles in plant biology (Pellny et al

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In fact, vitamin C is frequently added to many skin care products that purport to treat it