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During food preparation, chewing, and digestion, these phytochemicals are converted into biologically-active compounds, including dietary indoles and isothiocyanates , which are thought to help inhibit the development of degenerative diseases by controlling cellular overgrowth, as well as protecting the body against genotoxic agents

Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice

It is more common in in those with darker skin such as Mediterranean, Asian or Indian subtypes however all skin types can experience it

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Sherry E, Kitchener P, Smart R