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J Appl Electrochem 40:375382 Chen S-M, Lu M-F, Lin K-C (2005) Preparation and characterization of ruthenium oxide/hexacyanoferrate and ruthenium hexacyanoferrate mixed films and their electrocatalytic properties

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ROS not only directly oxidize tight junction proteins, inducing conformational changes and functional impairment, but also upregulate the expression and activity of MMP-9, thereby establishing a positive feedback loop that markedly accelerates the disintegration of tight junctions (152)

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