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Since mobile phase containing 0.1% OPA has a higher pH than the pKa of the NAC carboxylic group and placebo components, there are insufficient protons (H + ) in solution, and NAC dissociates into its conjugate base and become ionized, resulting in reduced retention, on RP-HPLC

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A collaborative team including Dr Khay-Yong Saw, Dr Reza Ng, Dr Caroline Jee (Kuala Lumpur Sports Medicine Centre, Malaysia), and Dr Adam Anz (Andrews Research and Education Foundation, Florida, USA) demonstrate the safety and efficacy of peripheral blood stem cell (PBSC) injections for treating damaged articular cartilage in a recently published clinical trial