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The authors research whether TB-500 may tone down this signaling and suggest that the peptide may increase the level of miR-146a, a small regulatory RNA molecule whose role may be to act as an internal brake on inflammatory signaling pathways

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Supporting this, erucamide treatment elevated CD11b + myeloid infiltration and upregulated trophic factors such as FGF, IGF-1 and BDNF, which may enhance synaptic function or resilience of bipolar and Mller cells

Compared with controls, Epitalon-treated cells display distinct structural changes consistent with its reported cytoprotective and regenerative effects