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Hepatic function had to be stable, defined as no clinically significant change in disease status, as judged by the investigator

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Diabetes Res 1987

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Charges belonging to atoms inherited from K1 Cagri were removed, and their sum (0.049e) was equally redistributed to the seven sp 3 carbon atoms bound to the terminal carboxy group to restore formal charge -1

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Proposed mechanisms for the induction of insulin resistance by oxidative stress

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